The most sustainable & affordable solution
for molecular interaction analysis
Pro series common features
Sample to Answer
After designing an experiment through the Experiment Wizard, when a sample is injected, the kinetics evaluation value can be obtained through the automatic analysis function built into the iMSPR operating software.
Sustainable U-type fluidics module
Through the U-type fluidics module, the immobilization step can be shortened efficiently, and referencing can be performed perfectly without time lag. In addition, it can be used permanently since it is manufactured with a PEEK unibody.
Inlet 1
Outlet
Inlet 2
U-type fluidics module
Sensor chip surface
Sample flow channel
Reference region
Ligand immobilization region
When using both channels (binding analysis)
When immobilizing the ligand
Automatic qualification check of sensor chip
The sensor chip status is checked before the experiment through the automatic check function built into the iMSPR operation software. You can secure more reliable data by checking initialization status.
In-line degassing system
If you use the iMSPR Pro series, degassing the buffer is unnecessary. The built-in degassing module reduces the failure rate of experiments by removing bubbles.
Pump
Vaccum
Removed bubbles
Sensor
Permeable tubing
What are the differences between iMSPR Pro Series
Pro2X
ProX
Pro
Sample flow channel
4
two experiments per chip
Fluidics module
UFD Fluidics module with dual U-type flow cells
Sample injection
Autosampler with dual injection valve
48 vials rack x 2
96 well plate x 2
Sample volume
(200ul sample loop)
Max 200ul
Partial injection available
30 ~ 75 ul dead volume
Screening capacity
300 samples per day
2
one experiment per chip
Standard Fluidics module with mono U-type flow cells
Autosampler with mono injection valve
48 vials rack x 2
96 well plate x 2
Max 200ul
Partial injection available
30 ~ 75 ul dead volume
150 samples per day
2
one experiment per chip
Standard Fluidics module with mono U-type flow cells
Syringe
One by one
Max 200ul
Partial injection available
30 ~ 60 ul dead volume
Not recommended
UFD fluidics module
1000 x 150 um
Flow cell cross section of Standard fluidics module
700 x 50 um
Flow cell cross section of UFD fluidics module
Compare with Standard fluidics
-
200 nl, 80% reduction of cell volume
-
Interval-less referencing
-
Lower consumption of sample
-
More accurate leveling of immobilization
Add options,
get powerful functions
Temperature control unit
In various temperature environments (10 to 40 degrees, room temperature dependent conditions), it is possible to obtain the value of the bonding properties and obtain the thermodynamic constants (enthalpy, entropy) through this. as well as biological temperatureThe binding properties of new drug candidates can be confirmed in the environment (37 degrees). Through this, predict the dynamics of the drug in the body and understand the bonding between molecules more completely.
10 C ~
o
40 C
o
Cooling unit
When a large amount of sample needs to be analyzed, drug candidates such as antibodies may be denatured due to the high temperature inside the autosampler. The cooling unit is a temperature cooling function inside the autosampler that can prevent this. It can cool down to 4 degrees, so you can safely analyze your samples until the end.
4 C
o
GxP Program
21 CFR compliance compliant programs can be installed.
21 CFR part 11
Premium maintenance program
If you upgrade to iMcare+, a premium maintenance/management program, you can extend the warranty period to 2 years, as well as receive regular inspection, SW upgrade, free replacement of consumables and free operation training for 10 years.
Specifications
Pro2X
ProX
Pro
Common Includings
Individual Includings
iMSPR-Pro main body (1 set), Prism holder (1ea), Detach tool (1ea), PC (1ea), SW (1cp), Flat tweezer (1ea), Matching oil (3ml), USB cable (1ea), Power cable (1ea)
UFD Fluidics module with dual U-type flow cells (1ea), Autosampler with dual injection valve (1ea), 48 vial rack (1ea), Vials of 750ul (1pk)
Standard Fluidics module with mono U-type flow cells (1ea), Autosampler (1ea), 48 vial rack (1ea), Vials of 750ul (1pk)
Standard Fluidics module with mono U-type flow cells (1ea), Syringe of 250ul (1ea)
Waranty
SPR system
1 years
SPR type
Angular interrogation, Prism coupling
Light source
Near IR LED
Detector
Association range
Dissociation range
Affinity range
2D CMOS image sensor (The detailed specification of each model is different.)
10
3
10
7
to
M
-1
s
-1
10
-5
1
to
s
-1
10
-3
10
-12
to
M
-1
Noise level
0.1 RU
Sample type
Small compounds, peptides, oligomers, lipids, proteins, cell-like molecules
DMSO resistance
10%