The most sustainable & affordable solution
for molecular interaction analysis
Multi-Array SPR System
for multiplex kinetics assay
iMSPR-PlexM
iMSPR-PlexM is an advanced SPR system designed for comprehensive multi-molecular binding analysis. With the ability to perform multiplexing assays of up to 250 analytes on a single chip, it delivers high-volume data in an exceptionally short time using only minimal sample amounts. By utilizing iMSpot, an automated spotter model developed by icluebio and optimized for SPR sensor chips, users can conveniently produce sensor chips with ligands arranged in customized configurations, tailored to their specific experimental needs.
PlexM is the optimal choice for screening candidate substances in the early stages of drug discovery and ensures highly efficient analysis in epitope studies and Fc receptor testing for antibody drugs.
Core Features
up to
250
interactions
for
10
minutes
less
1
microliter
With iMSpot, users can immobilize or capture ligand materials on the sensor chip in a precise spot pattern, tailored to their experimental needs. Using a 80 μm pin, up to 10 spots per unit area and a maximum of 250 spots can be arranged within a compact 5 x 5 mm ligand array zone. Once the sensor chip with ligand spots is mounted on the iMSPR PlexM, simply inject the analyte. This cutting-edge system enables the observation of up to 250 molecular interactions in just 10 minutes, offering unparalleled efficiency and throughput.
up to 250 spots/chip
10 spots / unit area
Multi-sensorgrams in 10 min
Maximize Efficiency with Minimal ligand Usage
Traditional SPR systems typically require around 200 μL to immobilize ligands in a single channel at concentrations ranging from 1–100 μg/mL. In contrast, iMSPR-PlexM revolutionizes this process with pin spotting technology, enabling the immobilization of multiple ligands on a single chip using less than 1 μL of sample at concentrations between 10–1000 μg/mL. With iMSPR-PlexM, you can significantly reduce ligand consumption while achieving precise and efficient results.
Sustainable hexagon type fluidics module
Through the hexagon(H)-type fluidics module, binding reactions can be performed with multiple ligands at once in a continuous flow manner. In addition, the H-type fluidics module can be used semi-permanently because it is manufactured as a PEEK-based unibody.
Streamline Drug Discovery with Advanced Kinetics Screening
The single-concentration kinetics screening function is highly effective during the early stages of drug discovery. Substances that meet or exceed the user-defined cut-off points for binding yield and kinetics values are highlighted in green, enabling users to easily identify hits from a large number of samples. For more precise evaluations, the system also supports experiments using multiple ligands at varying concentrations with a single analyte, delivering greater accuracy and deeper insights than single-concentration screening alone.
Specifications
PlexM
Includings
iMSPR-PlexM main system (1ea), Peristaltic pump with single channel (1ea), Degasser with single channel (1ea) H-type Fluidics module (1ea), Prism holder (1ea), Detach tool (1ea), PC (1ea),
Flat tweezer (1ea), Matching oil (3ml), USB cable (1ea)
Waranty
1 years
SPR system
SPR type
Reflect intensity measurement at fixed angle
Light source
Near IR LED
Detector
2D CMOS image sensor
Association range
10
3
10
6
to
M
-1
s
-1
Dissociation range
Affinity range
10
to
0.1
s
-1
10
-4
10
-11
to
M
-1
Noise level
1 RU
-5
Sample type
Small compounds, peptides, oligomers, lipids, proteins, cell-like molecules, Nano particles
DMSO resistance
10%